Open Macromolecular Genome (OMG)

The Open Macromolecular Genome (OMG) is a comprehensive polymer database designed for generative machine learning and synthetically accessible polymer design. OMG contains nearly 12 million chemically distinct constitutional repeating units (CRUs) generated from 77,281 commercially available monomer reactants using 17 canonical polymerization reactions. The database enables property-driven polymer design by providing synthetic pathways, purchasable reactants, and machine learning-compatible polymer representations.